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Alyra Therapeutics

Alyra TherapeuticsAlyra TherapeuticsAlyra Therapeutics

 Next-generation precision oncology 

Alyra Therapeutics

Alyra TherapeuticsAlyra TherapeuticsAlyra Therapeutics

 Next-generation precision oncology 

Who We Are

Where We Are

Who We Are

Headquartered in San Diego, CA with collaborators in Irvine, CA, Austin, TX and Genoa, Italy, we are a team of academic scientists and veteran pharmaceutical industry executives focused on developing novel first-in-class protein-protein interaction inhibitors for the treatment of cancer and rare diseases.

What We Do

Where We Are

Who We Are

Using an innovative drug discovery platform that integrates computational chemistry and both intracellular and biophysical assay technologies we have identified multiple inhibitors of the CDC42 and related families of protein switches that regulate growth and metastasis of cancer cells.

Where We Are

Where We Are

Where We Are

We are focused on our clinical lead compound, ALY101. A highly selective inhibitor of tumor growth and angiogenesis, ALY101 has activity against multiple tumor types in both in vitro and in vivo settings and has demonstrated the potential to impact the treatment of additional cancers as well as multiple rare diseases.


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